South San Francisco CA Real Estate & Homes for Sale

This expansive 3,160 sq. ft. single-family home sits in convenient South San Francisco with beautiful partial mountain views. It features an updated kitchen, partially refreshed baths, and two flexible bonus rooms ready to serve as an office, gym, nursery, theater, or extra bedrooms. The open floor plan is designed for relaxed everyday living, with a formal dining room well suited to entertaining. A rare extra-large 3-car garage (not included in the square footage) and washer and dryer connections on both the main floor and in the garage add to everyday convenience. Substantial living space and Peninsula convenience in one package. Welcome to your new home!

Located in South San Francisco, this 2-bedroom, 1-bathroom home offers 1,050 sq ft of living space on a 4,675 sq ft lot. The ground floor bedroom and laminate flooring throughout provide a practical layout. The kitchen features modern appliances including a dishwasher, garbage disposal, electric oven, and refrigerator. The bathroom includes a primary stall shower with tile finishes. The living room is enhanced by a fireplace, adding a cozy focal point to the space. Laundry facilities include an electricity hookup (110V). Additional interior features include a dining area and a video/audio system. The property includes a one-car garage and is located within the South San Francisco Unified elementary school district. No cooling system or pool is present.

High Rise Luxury Living at its finest. Million Dollar Views of the Bay and City Lights. Unbeatable location-very close to SF, the new Biotech hub in SSF, SFO, BART, 101/280. Bright and open living space. Modern kitchen with gas stove, stainless steel appliances, granite countertops. The large master bedroom also has panoramic views! Additional highlights include an in-unit washer/dryer, 2 assigned parking spaces & a secured storage locker. Located in a secure high-rise building, residents enjoy access to a fitness center, a social room, community terrace, elegant lobby & visitor parking. Close to restaurants along Downtown SSFs Grand Ave.

Beautifully refreshed and thoughtfully expanded, this impressive 3-bedroom, 2-bath residence offers approximately 1,870 square feet of inviting living space designed for both everyday comfort and effortless entertaining. A fresh interior and exterior color palette creates a crisp, sophisticated feel, complemented by newly installed and beautifully refinished hardwood flooring throughout. The updated kitchen features new countertops and appliances, offering a stylish and functional centerpiece for the home. Expanded over the years, the residence offers a wonderfully versatile floor plan with a spacious family room and enclosed patio providing additional areas to gather, entertain or simply unwind. Generous living spaces and an easy flow throughout the home create a sense of openness rarely found in a traditional three-bedroom residence. The transformation continues outdoors, where newly landscaped front and rear yards enhance the homes curb appeal and create attractive settings for outdoor dining, entertaining and relaxation. Freshly updated, exceptionally spacious and ready to enjoy, 343 Alta Mesa Drive presents a wonderful opportunity to experience elevated Peninsula living with the space and flexibility to make it truly your own.

Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.

Set against the scenic backdrop of San Bruno Mountain Ecological Reserve, well-maintained 2 BD, 2 BA corner penthouse offers 1,440 sqft of modern high-rise elegance w/ soaring ceilings. The grand lobby ft. a dazzling chandelier and sunlit lounge. Inside, open living & dining area is flooded w natural light, framed by sweeping mountain views through oversized windows. Hardwood floors run throughout, while plush carpet in the bedrooms adds warmth. The chef-inspired kitchen ft designer cabinetry, granite counters, and stainless steel appliances. The primary suite includes a walk-in closet with custom organization and a spacious bathroom. The second bedroom offers a comfortable, private feel, and an in-unit washer & dryer adds convenience. Additional perks: 2 dedicated parking spaces, guest parking, and access to fitness center, business center, clubroom, and landscaped patio. Key fob entry and a package room add security. As a corner unit, the home benefits from added natural light and extra windows. Location is unbeatable, minutes from Highway 101, with Costco, Oyster Point dining, and Marina Park's waterfront paths nearby. The San Bruno Mountain Ridge Trail begins right outside your door elevated comfort, timeless style, and one of the best lifestyles the Bay Area has to offer.

Opportunity awaits at 22 Sonora Avenue! This 3-bedroom, 1-bath home offers an efficient two-level floor plan and plenty of potential for its next owner. The main level features a light-filled living room with multiple windows, an eat-in kitchen, and one bedroom. Upstairs, you'll find two additional bedrooms connected by an open landing area beneath charming pitched ceilings. An attached one-car garage and generous backyard provide added space and possibilities. Owned by the same family for many years, the home is ready for its next chapter and an opportunity for a buyer to renovate and make it their own. Convenient South San Francisco location near shopping, transportation, and everyday amenities. Bring your vision and imagine the possibilities!

Nestled in the highly coveted Westborough Hills of South San Francisco, welcome to this spacious and inviting 4-bedroom, 3.5-bath well crafted home for comfortable living and entertainment in a three-level setting. Featuring generous living spaces with very high ceilings, well-appointed bedrooms, and modern bathrooms, this home offers the perfect blend of style, functionality, and convenience. The open and welcoming layout provides plenty of room for everyday living, while the four bedrooms offer flexibility for family, guests, or home office, with easy accessibility to a ground level bedroom and full bath. Top floor offers sweeping panoramic views where you can enjoy breathtaking sunrises every morning over the city skyline. The home offers a large back deck and a private estate entrance and security. Don't miss an opportunity to own property in the booming Biotech capital of California, just 10 minutes away midst the best part of the city and 10 minutes from scenic Highway 1 and ocean beaches. Regular sale with a clean and clear title history for an easy close of escrow.

Elevate your everyday routine at 1400 El Camino Real #220, a sleek and sunlit South San Francisco sanctuary designed for high-vibe Peninsula living. Delivering an effortless blend of modern comfort and low-maintenance style, the bright, open-concept layout flows seamlessly to accommodate your remote work setup, quiet relaxation, or weekend entertaining. Enjoy secure building amenities and dedicated parking in an unbeatable location along the iconic El Camino corridor putting you just minutes from SSF BART to commute to San Francisco, Caltrain, major biotech campuses like Genentech, and the vibrant local dining scene on Grand Avenue. LOCATION, LOCATION and LOCATION is noteworthy as it is in Close Proximity to the SSF BART, COSTCO Warehouse Store; Pacific Super Grocery; Trader Joes; Grocery Outlet: StarBucks and KAISER Hospital. Not to forget to mention its proximity to banks such as Bank of America, Citibank and Wellsfargo Bank located at the Chestnut shopping area. With fast access to Hwy 101 and 280 for seamless San Francisco or Silicon Valley trips, this home is the ultimate match for first-time buyers or savvy investors looking for location, light, and connected urban living. Bring your design vision, drop your bags, and start living your best South City chapter!

Welcome to 157 A Street, a charming South San Francisco home where classic character meets thoughtful updates. Beautifully refreshed with new interior and exterior paint and updated fixtures throughout, this inviting residence is polished, welcoming, and ready to enjoy from day one. Inside, natural light and original character create a warm sense of home. Beautiful parquet hardwood floors bring richness and charm to the living spaces, while the corner fireplace creates an inviting focal point and a cozy place to gather. The sunny eat in kitchen offers a cheerful setting for morning coffee, casual meals, and everyday living, while two comfortable bedrooms and a well-appointed bath complete the home's thoughtfully designed interior. Outside, a private yard offers a lovely extension of the living space, with room to relax, garden, or entertain. An attached garage with laundry hookups adds everyday convenience. Ideally situated near downtown South San Francisco, with easy access to shopping, dining, BART, Caltrain, SFO, and major commuter routes, 157 A Street offers an appealing combination of character, convenience, and move in ready comfort in the heart of the Peninsula.

Welcome to 107 Mulberry this charming home features living room wth fire place, shutters throughout home, original hardwood floors, It offers 3 Bedrooms 1 Bathroom, The bathroom has been recently remodeled with two car detached garage, long paved driveway for plenty of addl. parking. eat -in kitchen, new SS appliances, separate laundry room adjacent to kitchen. freshly painted interior & exterior. Blocks away is the Orange Memorial Park.

Why rent when you can own? Welcome to 811 Marcie Circle, South San Francisco spacious and well-maintained 1-bedroom, 1-bathroom lower-level home offering comfort, convenience, and exceptional value. The generous floor plan features a bright living area that opens to a private patio, creating the perfect space to enjoy your morning coffee, unwind after a long day, or entertain friends. The home also offers secure garage parking with one dedicated parking space and private lockable storage, providing added convenience and peace of mind. A shared washer and dryer are conveniently located in the garage just steps from your front door. With just a few steps down to the front door, everyday living is easy, making it convenient to carry groceries, luggage, and packages into your home. Ideally located near shopping, dining, parks, BART, Caltrain, major freeways, and South San Francisco's thriving biotech hub, commuting and everyday errands are a breeze. Whether you're a first-time homebuyer, downsizing, or looking for a great investment opportunity, this is your chance to stop renting and start building equity. Don't miss this wonderful opportunity to own a home in one of the Peninsula's most convenient locations!

Just reduced $50,000. This charming 3-bedroom, 2-bathroom home in South San Francisco offers a bright, easy layout ideal for everyday living. Downstairs, a spacious basement invites endless possibility a workshop, gym, media room, or extra storage, whatever suits your vision. Tucked in a convenient location near shops, dining, and commuter routes, this is a home ready to welcome its next chapter.

Welcome to this exceptional single-family residence ideally situated in the heart of South SF, offering the perfect blend of space, versatility, and convenience. Boasting approximately 2,360 square feet of living space (2665 sf including In-Law unit), this well-appointed home features 3 spacious bedrooms and 3 full bathrooms (4Bed/4Bath total), thoughtfully designed for comfortable everyday living. The functional layout offers generous living areas filled with natural light, creating a warm and inviting atmosphere throughout. Adding tremendous value is a separate approximately 300-square-foot in-law unit, ideal for extended family, guests, a private home office, or rental income potential. Enjoy an unbeatable location just moments from Orange Memorial Park and Sign Hill Park, where outdoor recreation, scenic walking trails, and breathtaking views await. Walk to vibrant downtown South San Francisco provides easy access to shopping, dining, cafes, and everyday conveniences. Whether you're seeking a spacious primary residence, multi-generational living, or an income-producing opportunity, this unique property delivers exceptional flexibility in one of South San Franciscos most desirable neighborhoods. Don't miss the chance to make this remarkable property your next home.

RARE NEW CONSTRUCTION! Discover modern luxury living in a brand-new condominium community ideally located across the road from the South San Francisco BART Station and next to Trader Joes. One-, two-, and three-bedroom floor plans are available, offering flexibility for a variety of lifestyles. Enjoy exceptional convenience with shopping, schools, hospitals, and public transportation nearby, while still coming home to a peaceful and quiet environment. The BART goes underground nearby, and triple-pane windows help block outside noise for added comfort. Each residence features high ceilings, large floor-to-ceiling windows, and bright open living spaces. Homes are thoughtfully finished with Samsung appliances, Daikin air conditioning, Hansgrohe faucets, Toto toilets, and owned solar panels for energy savings and everyday efficiency. Experience the perfect blend of luxury, convenience, and sustainability in South San Francisco. One-, Two- and three-bedroom model homes are available.

Located in South San Francisco's Braewood Westborough Community, this rarely available 3-bedroom, 1.5-bath townhome offers 1,200 square feet of comfortable living space. The kitchen features granite countertops, a gas oven range with hood, dishwasher, and refrigerator, ideal for everyday cooking and meal prep. Flooring throughout combines carpet and laminate, providing a mix of comfort and easy maintenance. Laundry is conveniently located inside the home and includes a washer and dryer. The dining area is integrated into the living room, and the bathrooms include a half bath on the ground floor and a full bath upstairs with a shower over tub. The property includes a one-car garage and driveway. On a clear day you can see the San Francisco Bay and the San Mateo Bridge from the master bedroom!

RARE NEW CONSTRUCTION! Discover modern luxury living in a brand-new condominium community ideally located across the road from the South San Francisco BART Station and next to Trader Joes. One-, two-, and three-bedroom floor plans are available, offering flexibility for a variety of lifestyles. Enjoy exceptional convenience with shopping, schools, hospitals, and public transportation nearby, while still coming home to a peaceful and quiet environment. The BART goes underground nearby, and triple-pane windows help block outside noise for added comfort. Each residence features high ceilings, large floor-to-ceiling windows, and bright open living spaces. Homes are thoughtfully finished with Samsung appliances, Daikin air conditioning, Hansgrohe faucets, Toto toilets, and owned solar panels for energy savings and everyday efficiency. Experience the perfect blend of luxury, convenience, and sustainability in South San Francisco. One-, Two- and three-bedroom model homes are available.

648 Newman Drive offers a spacious tri-level floor plan in the desirable Winston Manor neighborhood of South San Francisco. The main level features a bright living room, dining area with backyard access, and an updated kitchen conveniently located nearby. A sliding glass door connects the dining area to the backyard, creating an easy indoor-outdoor flow. The lower level includes a large family room with vaulted ceilings, exposed wood beams, and a fireplace, plus a wet bar with sink, full bathroom, and access to the attached two-car garage with ample storage. A second sliding glass door provides direct access to the backyard, making it ideal for entertaining. Upstairs, the private bedroom level features a primary suite with its own bathroom and walk-in closet, along with two additional bedrooms and a full hallway bathroom. The fully fenced backyard offers space for outdoor dining, gardening, pets, and recreation. Conveniently located near Highways 101 and 280, BART, Caltrain, SFO, shopping, dining, parks, and schools, this home combines generous living space with excellent commuter access.

RARE NEW CONSTRUCTION! Discover modern luxury living in a brand-new condominium community ideally located across the road from the South San Francisco BART Station and next to Trader Joes. One-, two-, and three-bedroom floor plans are available, offering flexibility for a variety of lifestyles. Enjoy exceptional convenience with shopping, schools, hospitals, and public transportation nearby, while still coming home to a peaceful and quiet environment. The BART goes underground nearby, and triple-pane windows help block outside noise for added comfort. Each residence features high ceilings, large floor-to-ceiling windows, and bright open living spaces. Homes are thoughtfully finished with Samsung appliances, Daikin air conditioning, Hansgrohe faucets, Toto toilets, and owned solar panels for energy savings and everyday efficiency. Experience the perfect blend of luxury, convenience, and sustainability in South San Francisco. Two- and three-bedroom model homes are available.

Welcome to 20 Maple Ave, a beautifully maintained Craftsman cottage blending early 20th-century character with modern updates. Situated on a desirable corner lot in "Old South SF," this two-bedroom home offers a warm atmosphere just steps from downtown. Step through the formal entry into a living room anchored by a stone fireplace. The home features hardwood floors, fresh paint, and updated lighting. The modern eat-in kitchen boasts quartz countertops, a farmhouse sink, and stainless appliances, while maintaining original charm. A dedicated mudroom and laundry area provide a practical transition to the outdoors. Enjoy a private retreat in the fenced backyard and patio, ideal for relaxing. The property includes a detached garage for secure parking. Located minutes from Grand Avenue, biotech hubs, and Caltrain, this home is a commuters dream. 20 Maple Ave is a rare find ,capturing the essence of California cottage living.

Tucked away in the heart of South San Francisco, this beautifully updated single-family home offers the perfect blend of modern style, comfort, and convenience. Step inside to a light-filled interior featuring refined finishes and an inviting floor plan designed for both everyday living and effortless entertaining. The updated kitchen boasts sleek countertops, contemporary cabinetry, and quality appliances, making it as functional as it is stylish. Spacious bedrooms provide a peaceful retreat, while the tastefully remodeled bathrooms showcase elevated finishes and a spa-inspired feel. Thoughtfully updated throughout, this home combines timeless design with everyday comfort in a highly desirable location.

Welcome to 55 Buena Vista Road, beautifully updated 4-bd, 3-ba home offering 2,490 sqft of thoughtfully designed living in the desirable Westborough. Step inside through an elegant marble foyer into a bright living area w/ soaring cathedral ceilings, expansive windows, and modern fireplace w/ floor-to-ceiling imported Spanish tile. The formal dining room ft stunning crystal chandelier & opens to a private deck, creating indoor-outdoor flow. The kitchen is designed for both everyday living & hosting, complete w/ high-end granite countertops, premium cabinetry, a spacious island & designer lighting. It connects effortlessly to the family room, creating a warm & functional gathering space. A full ba on the main level adds flexibility for guests. Upstairs, plush carpeting adds comfort throughout four spacious bds, including a luxurious primary suite w/ a freestanding tub, walk-in shower, and elegant imported tile finishes. A dedicated laundry room and guest bathroom w/ double vanity and mosaic tile accents complete the upper level. Outdoor living is enhanced by a private deck accessible from multiple bedrooms, along w/ 2-car garage + EV charger for modern convenience. Located across from Sellick Park, plus close proximity to Westborough Square, local amenities, and I-280.