The median home value in South San Francisco, CA is $1,275,000.
This is
lower than
the county median home value of $1,500,000.
The national median home value is $308,980.
The average price of homes sold in South San Francisco, CA is $1,275,000.
Approximately 58% of South San Francisco homes are owned,
compared to 38% rented, while
4% are vacant.
South San Francisco real estate listings include condos, townhomes, and single family homes for sale.
Commercial properties are also available.
If you like to see a property, contact South San Francisco real estate agent to arrange a tour today!
Learn more about South San Francisco.
MISSION-CRITICAL BIOTECH - FULLY SECURED - FEDERAL TENANT. A premier 21,552 SF high-tech facility purpose-built in 2019. This 3.65-acre site in the heart of the global biotech cluster offers specialized laboratory infrastructure, advanced security, and immediate access to the Bay Areas major transit corridors. The interior features approx. 9,500 SF of professional office, 4,500 SF of mission-critical lab space, and a 7,000 SF warehouse/inspection zone. The build-out includes multiple entomology and botany labs with phenolic resin countertops, 100% ducted exhaust (8 air changes/hour), and high-purity reverse osmosis water systems. A 500kW stand-alone diesel generator and dedicated UPS backup power ensure operational continuity. Logistics are streamlined via 4 interior dock-high doors within a secure devanning area for 53-foot tractor-trailers. This Security Level II facility is fortified with a Lenel card reader system, 24-hour CCTV, shatter-resistant blast-mitigation windows, and a fenced parking area with 62 assigned spaces. With its sophisticated technical build-out and a credit-tenant government lease, this asset represents a rare opportunity in the SSF Life Science submarket. Do not miss this opportunity!
Units 4 and 5 are currently combined via two interior openings: one located within the groundfloor front office area and a second opening on the second floor, also within the office area. Unit 4 features two ground-floor offices and a connecting hallway linking Units 4 and 5. A rear service room between the office area and warehouse contains two ADA-compliant restrooms and a stairwell providing access to the second floor. The second floor includes a conference room situated above the warehouse, followed by a work area equipped with a garage door opening over the warehouse for convenient forklift access. Two additional offices are located at the front of the second floor, along with another hallway connecting Units 4 and 5. Commercial Owners' Association (COA) is $817 a month.
Unit 3 encompasses approximately 2,208 square feet and is thoughtfully laid out to support a wide range of industrial and business uses. The space features a prominent front office with an upper-level, providing a professional client-facing presence, complemented by a spacious central warehouse ideal for storage, production, or distribution. A dedicated shipping and receiving area with a 16-foot overhead coiling door allows for efficient loading and logistics. The unit is further enhanced by two ADA-compliant restrooms, offering added convenience for staff and visitors. Commercial Owners' Association (COA) is $817 a month.
Units 4 and 5 are currently combined via two interior openings: one located within the groundfloor front office area and a second opening on the second floor, also within the office area. Unit 5 features a reception area, a ground-floor office, and a connecting hallway linking Units 4 and 5. The warehouse area includes two ADA-compliant restrooms, a stairwell providing access to the second-floor offices, and a separate staircase leading to the storage mezzanine. The second floor offers four offices, including two located toward the rear above the warehouse-- one with direct access to the mezzanine--and two front-facing offices with windows overlooking the parking lot. An additional hallway on the second floor also connects Units 4 and 5. Wall Opening to Unit 4. Commercial Owners' Association (COA) is $817 a month.
The property offers approximately 3,930 rentable square feet situated on a 5,081 square foot parcel. Originally built in 1966, the building features concrete block construction with a flat roof. Key features include approximately 10% finished office space, a 200-square-foot unfinished mezzanine, and separate men's and women's restrooms. The building is equipped with 3-phase, 200-amp electrical service. Additional highlights include a clear ceiling height of 13'7" and a front roll-up door measuring 12' high by 11'5" wide, providing excellent functionality for light industrial uses.

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